דיווח עצמי לעומת קליני על עיניים יבשות

Introduction:

Dry Eye Syndrome (DES) is a common complaint in ophthalmology and is defined as a chronic and progressive multifactorial disorder of the ocular surface, which results in symptoms of discomfort and visual disturbance and potential damage to the ocular surface (McDonald et al., 2015). In this cross-sectional study, we examined the correlation between self-reported dry eyes to the objective tests results in DES cases vs. controls, in contact lens (CL) wearers vs. non-CL wearers (N-CL), and in post refractive surgery (P-RS) vs non-refractive surgery (N-RS) subjects.

Methods:

88 healthy subjects (64 females, 44 DES cases, 44 age-and-sex matched) age range of 18-34, (mean age of 23.97 ± 3.36 years) participated in the study. One eye of each participant was tested, using TBUT and Ocular Surface Disease Index (OSDI) questionnaire. Dry eye subjects had TBUT test-less than 5 sec and/or OSDI score >25 points. Analysis was performed using Pearson's correlations and Independent Samples T-test.

Results:

Mean TBUT result was higher on controls than DES cases (7.57±2.34 vs. 3.14±0.90 respectively; p<0.001), and OSDI score was higher on DES cases vs. controls (28.76±4.52 vs.8.41±6.51 respectively; p<0.001).
There is slight and Negative correlation between TBUT and OSDI among DES cases and controls (r=-0.62; p<0.001) was found. There was no difference in TBUT between CL and N-CL wearers (p=0.53). Due to low number of patients after refractive surgery (N=4) and CL wearers (N= 22), no correlation was found between signs and symptoms in those groups.

Conclusions:

OSDI questionnaire is not interchangeable to TBUT test on DES and NON-DES patients, implying there is not much of association between signs of dry eyes and the reported symptoms.

מרכזת המחקר לתואר ראשון: ד"ר עינת שניאור